Abstract Pyrazinamide is an antituberculosis agent. It works by killing or preventing the growth of certain bacteria that cause tuberculosis. HPLC and UV method was employed for the estimation of Pyrazinamide in pharmaceutical formulations. A mixture of Methanol: Water in the ratio of 80:20 (v/v/v) at a pH of 4.8 in isocratic conditions and separation…
Abstract Risperidone is a potent antipsychotic drug which is mainly used to treat schizophrenia and schizoaffective disorder. A new isocratic HPLC method was developed for analysis in formulations. The developed method was validated according to ICH guidelines. The method was developed with the mobile phase 0.1% OPA: Methanol:Acetonitrile in the ratio of 60:25:15(V/V/V). In this method the back pressure was…
Abstract Rosmarinusofficinalis is one among the phenomenon herb. This wonder herb has numerous health benefits which sometimes outshined. As a health contributor rosemary has attracted many herbal manufacturer as well as suppliers. Its different forms such as oil, powder, cream etc gives an extra edge to this herb in comparison to others. The present review…
Abstract To avoid consume theophylline oftenly, we need an extended release dosage form to maintain the therapeutic dose on the blood plasma for a long interval time. The most common dosage form in the market is coated tablet, but that needs a long procedure and quite expensive to be produced. Recently, there is a brand…
Abstract This study aims to discuss the criteria adopted by the Brazilian legislation on the patentability of pharmaceutical products at the National Institute of Industrial Property, as well as the obligation to submit the application to a prior consent from the National Health Surveillance Agency, due to the great social importance of the theme of…
Abstract Simple and cost effective UV and Visible spectroscopic methods were described for the estimation of Haloperidol in Phamaceutical dosage forms. Visible method was based on the formation of organic solvent extractable ion association complex with ARS dye. In both methods the solutions showed maximum absorption at 248nm, 495nm; also obeyed Beer’s law in the…
Abstract A rapid, sensitive and selective analytical Liquid chromatography tandem mass spectrometrymethod was developed and validated for the determination Telmisartan and Hydrochlorothiazidein human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compounds were analyzed on a Aquasil-C18 (250×4.6mm×5µm) column with the mobile…
Abstract The aim of the present work was to develop simple, shorter and effective HPLC method with UV detection (255 nm) and subsequent validation for the simultaneous determination of Avibactam and Ceftazidime in marketed tablet samples. The mobile phase consisted of 1% OPA: Acetonitrile 55:45 (v/v) [pH 5.5], an isocratic elution at a flow rate…
Abstract There is worldwide interest in silver nanoparticles (AgNPs) synthesized by various chemical reactions for use in applications exploiting their antibacterial activity, even though these processes exhibit a broad range of toxicity in vertebrates and invertebrates alike. To avoid the chemical toxicity, biosynthesis (green synthesis) of metal nanoparticles is proposed as a cost-effective and environmental…
Abstract ACTINOMYCETES are micro organisms with high medicinal activities. In many places research work going on inthis organism. So many Microbiologists isolated new and existed species from different environment soil. In order toidentification and isolation of Actinomycetes we are selected marine soil from Nazam patnam Port, Guntur Distric, Andrapradesh, India