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Most Effective Utility Function for HIV Drug using Cost and Efficacy Analysis

Abstract The fight on HIV/AIDS globally is on increase everyday.  Many research activities are pioneered to put the scourge under control.  In the present paper an exposition is made on the need to fight HIV/AIDS is presented and the role which Operations Research experts can play to reinforce research on HIV/AIDS. The paper also considers…

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A New Method Development and Validation for Analysis of Rivaroxaban in Formulation by RP HPLC

Abstract A new simple, rapid, selective, precise and accurate isocratic reverse phase high performance liquid chromatography assay has been developed and validated for the estimation of Rivaroxaban in tablet formulation. The separation was achieved by using C-18 column (250×4.6mm, 5µm in particle size) at ambient temperature coupled with a guard column of silica in mobile…

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Rosemary, (Rosmarinus Officinalis) Linn. An Updated Review

Abstract Rosmarinus officinalis L. also called as Rosemary is an evergreen perennial shrub native to Southern Europe and has been cultivated in all Braziliian states. Rosmarinus officinalis L belongs to Lamiaceae/Labiatae family, which posses various medicinal healing properties for human life. Traditionally parts like leaves, flowers and stems are being used in the treatment of…

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An Updated Review on Alzheimer’s Disease

Abstract Preliminary data support the hypothesis that the decline of all higher cognitive functions in senile dementia of the Alzheimer type is attributable to histopathological changes in the hippocampal formation, with or without neocortical neuronal lesions[1]. Alzheimer’s disease is the most common form of dementia (non-specific syndrome in which affected areas of brain function may…

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Pharmacognostic authentication and constituents’ validation by HPLC for four different plant species of Vidari marketed in India

Abstract The aim of the present study is to use detail diagnostic characters and instrumental validation for authentication of a traditionally important herbal drug known as “Vidari” in local Indian market. Vidari drug has four different botanical entities namely Pueraria tuberose DC (P.t) (family: Leguminosae), Ipomoea mauritiana Jacq (I. m) (family: Convolvulaceae), Adenia hondala de…

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Dissolution Profile of Theophylline Extended Release Caplets Based On Metolose 90 SH – 4000SR With Accelerated Stability Study

Abstract To avoid consume theophylline oftenly, we need an extended release dosage form to maintain the therapeutic dose on the blood plasma for a long interval time. The most common dosage form in the market is coated tablet, but that needs a long procedure and quite expensive to be produced. Recently, there is a brand…

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The Legal System of Pharmaceutical Patents in Brazil

Abstract This study aims to discuss the criteria adopted by the Brazilian legislation on the patentability of pharmaceutical products at the National Institute of Industrial Property, as well as the obligation to submit the application to a prior consent from the National Health Surveillance Agency, due to the great social importance of the theme of…

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RP-HPLC Method Development and Validation for the Analyisis of Ezogabine in Pharmaceutical Dosage Forms

Abstract A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for assay of Ezogabine in tablet dosage form. Isocratic elution at a flow rate of 1ml min-1 was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Methanol:Water:Acetonitrile 30:50:20 (v/v/v). The UV detection wavelength was at…

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Identification of Anti‐Diabetic Activity of Strychnous Nuxvomica Roots in Invivo Conditions

Abstract Strychnous nuxvomica is a medicinal plant with many chemical constituents like strychnine, brucine, indole alkaloids etc. This study was design to investigate the effect of aqueous methanol extract of nuxvomica roots, on various biological parameters in diabetes induced rabbits. The effect of crude nuxvomica root and its organic extracts on blood glucose level of…

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New Spectrophotometric Method for Analysis of Erubulin in Pharmaceutical Dosage Forms

Abstract A simple, sensitive and economical spectrophotometric method has been developed for the determination of Erubulin in commercial dosage forms.In this method ferric chrloride and Potassium ferricyanide were used for the colour development.The maximum absorbance was found at 410nm against the reagent blank treated similarly.Statistical analysis proves that the proposed method is reproducible and selective…