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Validated UV and Visible Spectrophotometric Methods for the quantification of Haloperidol in Pharmaceutical dosage forms

Abstract Simple and cost effective UV and Visible spectroscopic methods were described for the estimation of Haloperidol in  Phamaceutical dosage forms. Visible method was based on the formation of organic solvent extractable ion association complex with ARS dye.  In both methods the solutions showed maximum absorption at 248nm, 495nm; also obeyed Beer’s law in the…

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Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of Telmisartan and Hydrochlorothiazide in Plasma

Abstract A rapid, sensitive and selective analytical Liquid chromatography tandem mass spectrometrymethod was developed and validated for the determination Telmisartan and Hydrochlorothiazidein human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compounds were analyzed on a Aquasil-C18 (250×4.6mm×5µm) column with the mobile…

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Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Avibactam and Ceftazidime in Bulk drug and injection dosage Form

Abstract The aim of the present work was to develop simple, shorter and effective HPLC method with UV detection (255 nm) and subsequent validation for the simultaneous determination of Avibactam and Ceftazidime in marketed tablet samples. The mobile phase consisted of 1% OPA: Acetonitrile 55:45 (v/v) [pH 5.5], an isocratic elution at a flow rate…

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RP‐HPLC Method Development And Validation for the Analysis of Vendetanib in Phramaceutical Dosage Forms

Abstract A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of VENDETANIB in tablet dosage form. Isocratic elution at a flow rate of 1ml min-1 was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile:ethylalchol:NH4H2PO4 60:25:15(v/v/v).The UV detection wavelength was at 219nm. Linearity…

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Effect of Time, Ph, And Doses to Obtain In Vitro Efficient Fibrinolysis with a New Microplasmin. Importance of Results for Future In Vivo Studies

During the coagulation of the blood is important the age of the clot, because the fibrin mesh becomes more compact.