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UV- Visible Spectrophotometric Estimation of Olmesartan in Pharmaceutical Dosage Form

Abstract

A simple spectrophotometric method based on single wavelength spectroscopy has been developed for the olmesartan in different pharmaceutical dosage forms.The method is based on the simple solubility of olmesartan in methanol.The absorbance maximum of Olmesartan was measured at wave length 271nm and 731nm for the UV method and visible method. Both the methods obeyed Beer-Lambert’s law over the concentration range 1-10 µg/ml and 0.5-3 µg/ml. The proposed method was successfully applied to the determination of Olmesartan in pharmaceutical dosage forms and the results tallied well with the label claim.

Issue

Research Desk 2016 Volume-5

Article Subject:

Chemistry

Keywords:

Olmesartan, UV spectrophotometer, Folin-Ciocalteus reagent, Olsertan, Olmetrack, Olmezest

Download PDF:

J Uma rao Research Desk, 2016, 5(1). 573-578

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