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LCMS Method Devlopment and Validation of Paliperidone in Formulation Dosage

Abstract A simple, precise and accurate RP-HPLC method was developed and validated for rapid assay of Paliperidone tablet dosage form. Isocratic elution at a flow rate of 1ml/min was employed on a symmetry Chromosil C18 (250×4.6mm, 5µm in particle size) at ambient temperature. The mobile phase consisted of Methanol: Acetonitril: Water 60: 10: 30 v/v,…

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A Novel RP-HPLC Method for the Determination of Capecitabine in Pharmaceutical Drug Products

Abstract A simple, precise and accurate RP-HPLC method was developed and validated for rapid assay of Capecitabine in tablet dosage form. Isocratic elution at a flow rate of 1ml/min was employed on a symmetry Chromosil C18 (250×4.6mm, 5µm in particle size) at ambient temperature. The mobile phase consisted of Methanol:Water 80: 20 v/v, (PH 4.9)….

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A New Method Development and Validation for Analysis of Rivaroxaban in Formulation by RP HPLC

Abstract A new simple, rapid, selective, precise and accurate isocratic reverse phase high performance liquid chromatography assay has been developed and validated for the estimation of Rivaroxaban in tablet formulation. The separation was achieved by using C-18 column (250×4.6mm, 5µm in particle size) at ambient temperature coupled with a guard column of silica in mobile…

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A Novel RP-HPLC Method for the Quantification of Tadalafil in Formulations

Abstract A simple, precise and accurate RP-HPLC method was developed and validated for rapid assay of Tadalafil tablet dosage form. Isocratic elution at a flow rate of 1.3ml/min was employed on a symmetry Chromosil C18 (250×4.6mm, 5µm in particle size) at ambient temperature. The mobile phase consisted of Methanol: Acetonitrile 65:35 v/v. The UV detection…

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RP-HPLC Method for the Quantification of Vismodegib in Formulations

Abstract Asimple, precise and accurate RP-HPLC method was developed and validated for rapid assay of Vismodegib in tablet dosage form. Isocratic elution at a flow rate of 1 ml/min was employed on a symmetry Chromosil C18 (250×4.6mm, 5µm in particle size) at ambient temperature. The mobile phase consisted of Methanol: water: Acetonitrile 55:25:20 % (V/V)….

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Validated RP – HPLC Method for the Estimation of Denosumab in Formulation

Abstract A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Denosumab in tablet dosage form. Isocratic elution at a flow rate of 1.0ml/min was employed on a symmetry C18 (250×4.6mm, 5μm in particle size) at ambient temperature. The mobile phase consisted of methanol: water: O.P.A 90:10:01 (V/V/V)….