LCMS Method Devlopment and Validation of Paliperidone in Formulation Dosage
Abstract A simple, precise and accurate RP-HPLC method was developed and validated for rapid assay of Paliperidone tablet dosage form. Isocratic elution at a flow rate of 1ml/min was employed on a symmetry Chromosil C18 (250×4.6mm, 5µm in particle size) at ambient temperature. The mobile phase consisted of Methanol: Acetonitril: Water 60: 10: 30 v/v,…