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New method development and validation for Simultaneous determination of 3 terpenoids (Terpineol, Limonene, α-Terpinene) in Black cardamom by HPLC

Abstract A HPLC method was developed and validated for simultaneous determination of Terpineol, Limonene, α-Terpinenein Black cardamom using a Hypersil bds C18column (250 mm×4.6 mm, 5 μm) with the mobile phase consisting of Methanol and 0.1% triethylamine,0.05M KH2PO4used as mobile phase in the ration of 45%,10%,45%  The linear ranges of three compounds were determined and method…

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Pharmacognostic authentication and constituents’ validation by HPLC for four different plant species of Vidari marketed in India

Abstract The aim of the present study is to use detail diagnostic characters and instrumental validation for authentication of a traditionally important herbal drug known as “Vidari” in local Indian market. Vidari drug has four different botanical entities namely Pueraria tuberose DC (P.t) (family: Leguminosae), Ipomoea mauritiana Jacq (I. m) (family: Convolvulaceae), Adenia hondala de…

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HPLC and UV Spectrophotometric Estimation of Pyrazinamide in Pharmaceutical Formulations

Abstract Pyrazinamide is an antituberculosis agent. It works by killing or preventing the growth of certain bacteria that cause tuberculosis. HPLC and UV method was employed for the estimation of Pyrazinamide in pharmaceutical formulations. A mixture of Methanol: Water in the ratio of 80:20 (v/v/v) at a pH of 4.8 in isocratic conditions and separation…

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Development and Validation of RP-HPLC Method for the Simultaneous Estimation of Avibactam and Ceftazidime in Bulk drug and injection dosage Form

Abstract The aim of the present work was to develop simple, shorter and effective HPLC method with UV detection (255 nm) and subsequent validation for the simultaneous determination of Avibactam and Ceftazidime in marketed tablet samples. The mobile phase consisted of 1% OPA: Acetonitrile 55:45 (v/v) [pH 5.5], an isocratic elution at a flow rate…

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RP-HPLC Method Development and Validation for the Analyisis of Ezogabine in Pharmaceutical Dosage Forms

Abstract A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for assay of Ezogabine in tablet dosage form. Isocratic elution at a flow rate of 1ml min-1 was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Methanol:Water:Acetonitrile 30:50:20 (v/v/v). The UV detection wavelength was at…

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RP‐HPLC Method Development And Validation for the Analysis of Vendetanib in Phramaceutical Dosage Forms

Abstract A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of VENDETANIB in tablet dosage form. Isocratic elution at a flow rate of 1ml min-1 was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile:ethylalchol:NH4H2PO4 60:25:15(v/v/v).The UV detection wavelength was at 219nm. Linearity…