An Updated Review on Alzheimer’s Disease

Preliminary data support the hypothesis that the decline of all higher cognitive functions in senile dementia of the Alzheimer type is attributable to histopathological changes in the hippocampal formation, with or without neocortical neuronal lesions[1]. Alzheimer’s disease is the most common form of dementia (non-specific syndrome in which affected areas of brain function may be affected ; such as memory, language). It was first described by German psychiatrist and neuro-pathologist, Alois Alzheimer in 1906 and was named after him. Research indicates that the disease is associated with plagues and tangles in the brain[2].