Article Subject

An improved synthesis of N-substituted imides can be achieved from the reaction of anhydrides (phthalic, maleic & succinic.) with pre-melted anilines by grinding at room temperature in the absence of solvents. The advantages of this method are good yields, shorter reaction times, low cost and matching with green chemistry protocols.

Phthalic anhydride
Maleic anhydride
Succinic anhydride and anilines.
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